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Hyperbaric oxygen therapy: pressure, oxygen and the chamber

What happens inside a hyperbaric chamber, described as physics and as operation: pressure, oxygen, the session, the people who run it and what a center plans for. Hipertech manufactures the chambers; how they are used clinically is decided by physicians.

Oxygen at a pressure above sea level

Hyperbaric oxygen therapy (HBOT) means breathing 100% oxygen at a pressure higher than the atmosphere at sea level, inside a pressure chamber.

The chamber is a pressure vessel for human occupancy (PVHO): it holds the pressure, and the occupants breathe the oxygen through a mask or a hood. The session pressure, the breathing gas and the length of each session are set by the physician responsible for the chamber.

Henry’s law and Boyle’s law

Two laws of gas physics describe what pressure does inside a chamber. They are stated here as physics only.

More pressure, more dissolved gas

The amount of a gas that dissolves in a liquid rises with that gas’s pressure. Breathing 100% oxygen above 1 ATA therefore dissolves more oxygen in the blood plasma than breathing air at sea level, and the amount keeps rising with the pressure.

Oxygen dissolved in plasmaTwo rising straight lines. Breathing air, dissolved oxygen in plasma rises from about 0.3 mL per 100 mL at 1 ATA to about 1.3 at 3 ATA. Breathing 100% oxygen, it rises from about 2.0 at 1 ATA to about 6.5 at 3 ATA.mL of oxygen per 100 mL of plasma02461.01.52.02.53.0Pressure, ATA0.84.31.26.1Breathing 100% oxygenBreathing air

Calculated with the alveolar gas equation and Henry’s law, the method stated in the HBOT Guide. Dissolved oxygen only: the chart does not show the oxygen carried by haemoglobin.

More pressure, less volume

At a constant temperature, the volume of a fixed amount of gas falls as its pressure rises: double the absolute pressure and the volume halves. A gas space that fills 100% of its volume at sea level fills 50% at 2 ATA, about 36% at 2.8 ATA and about 33% at 3 ATA.

Volume of a fixed amount of gasBars for 1, 2, 2.8 and 3 ATA at 100%, 50%, 36% and 33% of the sea-level volume.1 ATAsea level100%2 ATAabout 10 m50%2.8 ATAabout 18 m36%3 ATAabout 20 m33%

Boyle’s law for an ideal gas at constant temperature.

Pressure and depth

Chamber pressure is stated in atmospheres absolute (ATA). 1 ATA is the pressure of the atmosphere at sea level, and each 10 m of seawater adds about 1 ATA, so a chamber at 2 ATA holds the pressure found about 10 m down and a chamber at 2.8 ATA the pressure about 18 m down.

Pressure, ATASeawater depth equivalent
1.0Sea level, 0 m
2.0About 10 m
2.8About 18 m
3.0About 20 m

Points on the scale, not session pressures or a chamber rating.

How a session is run in a hyperbaric chamber

A session is a pressure cycle the operator runs from outside the chamber: compression, a period at session pressure while the occupants breathe oxygen, then decompression. The pressure, the breathing gas and the length of each session are set by the physician responsible for the chamber.

Pressure over time during a sessionFlat at 1 ATA while the occupants enter, a gradual rise to session pressure, a long flat period at that pressure in which oxygen alternates with short air breaks, then a controlled fall back to 1 ATA. The height of the session pressure is schematic; the axes show the ATA scale and its seawater depth equivalent, not a protocol or a chamber rating.ATADepth3.020 m2.010 m1.00 mGasTimeOxygenAirSession pressure, schematic12345
  1. The occupants go in at sea-level pressure. In a multiplace chamber the patients take their seats with a medical attendant inside; in a monoplace the single patient lies on a height-adjustable stretcher that runs into the hull, and the door is closed and locked.

  2. The operator raises the pressure gradually, so the occupants can equalize their ears as it rises. Pressure is stated in atmospheres absolute (ATA): 1 ATA is sea-level pressure, and each 10 m of seawater adds about 1 ATA, so 2 ATA is the pressure about 10 m down and 2.8 ATA the pressure about 18 m down.

  3. At session pressure the occupants breathe 100% oxygen. Each patient breathes it through a mask or a hood while the chamber itself holds compressed air, in a monoplace as in a multiplace. Under pressure more oxygen dissolves in the blood plasma than at sea level, because the amount of a gas that dissolves in a liquid rises with its pressure (Henry’s law).

  4. Where the physician’s protocol includes them, the occupants come off oxygen at set intervals and breathe air for a short period before going back on oxygen. The pressure does not change during an air break.

  5. At the end of the session the operator brings the chamber back down to 1 ATA at a controlled rate, and the occupants leave once it is at sea-level pressure.

Monoplace or multiplace

Hipertech builds both kinds of medical chamber. Which one a center needs follows from how many people it seats at once, whether staff work inside it, and the room it has.

Inside a Multiplace Omega: two rows of seats down the aisle, a breathing hose and a head harness at each seat
A Monoplace chamber installed in a hospital room, its control head with a touchscreen and gauges on top of the hull
Multiplace: Omega and QuadroMonoplace
OccupantsSeated patients with medical attendants inside, written as patients + attendants: Omega standard configurations run from 4+2 to 14+2One patient, lying on a height-adjustable stretcher
Chamber atmosphereCompressed airCompressed air
OxygenThrough a mask or a hood at each seatThrough a mask
Inside with the patientsA medical attendantNo one; the chamber is worked from outside
HullOmega: omega-shaped section, a cylinder cut flat at the floor. Quadro: rectangular sectionFull-clear or semi-clear acrylic or Lexan hull, to ASME PVHO
AccessQuadro: a 120 cm door with lightweight ramps for ICU stretchers, and a low threshold for wheelchairsAn internal stretcher that runs fully out of the open end
ControlHiperFlow: a 6-screen control desk on the Omega, a customised automation option on the QuadroHiperFlow automation system, with an operator panel at the chamber
RoomA chamber room with the plant behind itA room the hospital already has, with power, a gas supply and an access route the hull will pass through

The people who run a session

Roles

A physician in a white coat and a staff member in blue scrubs talking beside a chamber and its control panel
Physician
The physician responsible for the hyperbaric service selects the patients and sets each session’s protocol: the pressure, the breathing gas and the length of the session.
Chamber operator
Runs the chamber from outside it, at the HiperFlow control desk or the monoplace’s operator panel, through compression, the time at pressure and decompression.
Inside attendant
In a multiplace chamber a medical attendant sits inside with the patients; the second figure in a configuration such as 12+2 counts the attendants.
Technicians
Keep the chamber’s air and oxygen supply, fire suppression and control system in service.
Hipertech Academy
Medical, technical, maintenance and safety training for these roles, with certification by Hipertech on completion. Training runs online or on site: at the customer’s chamber after installation, or at HBO Group’s centers in İstanbul, where trainees observe live sessions.

Safety systems and the standards behind them

Every Hipertech medical chamber is designed and manufactured to EN 14931, ASME PVHO, NFPA 99, the Pressure Equipment Directive 2014/68/EU and the Medical Device Regulation (EU) 2017/745, under an EN ISO 13485:2016 quality system, and carries the CE mark. The safety systems differ by family and are listed for each family separately.

Safety systems, per family

Multiplace Omega
Constant oxygen concentration monitoring, AI patient surveillance at every seat, three-stage fire suppression to EN 16081 and NFPA 99.
Multiplace Quadro
Three-stage fire suppression to EN 16081 and NFPA 99, under the HiperFlow automation system.
Monoplace
An O₂ analyser with over-limit alarm, a fire fighting system to NFPA 99, a patient alarm and quick-stop button, a safety door lock, an emergency depressurisation valve, and a data-logger that keeps session records for up to two years.

Planning a center: room, gas supply, staff and readiness

The physician decides who is seen and at what pressure; the chamber, the room and the team have to be ready for what that physician prescribes.

What a center plans for

Room and plant
Power, a gas supply and an access route the hull will pass through; for a multiplace chamber, a plant room as well.
Gas supply
Oxygen for the masks or hoods, and compressed air for the chamber atmosphere, in a monoplace as in a multiplace.
Staff
A responsible physician, a chamber operator, an attendant for multiplace sessions and technicians for the plant, trained through Hipertech Academy.
Readiness
A center that accepts emergency referrals needs a chamber it can staff and pressurize at any hour, which shapes the choice of chamber, the staffing rota and the training plan as much as the room does. Which referrals a center accepts is a clinical decision for its physicians.
Turnkey projects
Hipertech develops turnkey HBO center projects around the Multiplace Omega.
The plant room of a delivered center: two Hipertech air receivers with copper pipework, a compressor and a refrigerated dryer

Medical societies, not chamber manufacturers, define what hyperbaric oxygen therapy is used for

Medical societies such as the Undersea and Hyperbaric Medical Society (UHMS) and the European Committee for Hyperbaric Medicine (ECHM) publish and review the conditions for which HBOT is used. Hipertech manufactures the equipment and makes no claims about those uses; whether a chamber is used, for whom and at what pressure is decided by the physician responsible for it.

Türkiye’s first private HBOT center, and the factory that followed

Op. Dr. Aytunç Yur, a general surgeon, and Prof. Dr. Ender İnci, an ENT surgeon, encountered hyperbaric oxygen therapy in 1995 and opened Türkiye’s first private HBOT center in 1997. It grew into HBO Group, which runs seven centers, and in 2005 they founded Hipertech to manufacture the chambers themselves. HBO Group’s centers are also where Hipertech customers train.

Plan the chamber with engineering

Say which family you are weighing and the room it has to fit, and the enquiry goes to engineering in İstanbul.

Talk to engineering